Integrated System
Integrated System
- Analysis of tissue characteristics and diagnosis/treatment factors for each target disease
- Establishment of medical microrobotics diagnosis/treatment scenario by disease
- Optimal medical microrobotics design considering characteristic analysis
- Application of optimal common ground module combination technique by disease
- Production of optimal medical microrobotics integrated system by disease
- Common ground module and prototype of medical microrobotics for treatment of solid cancer, circulatory and digestive system
Optimized medical microrobotics Integrated System for Solid Cancer
| Drive Module |
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| Carrier Module |
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| Diagnosis & Treatment Module |
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| Recognition & Visualization Module |
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- Fixed Electromagnetic Actuation Module
- - Actuation module for affected areas such as liver, lung, pancreas
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- Ultrasonic Actuation Module
- - Suitable for NK cell carrier focused drive without magnetic particles
- Simple and light hand-held method
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- NK cell Carrier Module
- - Non-toxic carrier module carrying solid cancer treatment drug
- Adds the effect of drugs to NK cell's function of killing cells
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- Micro-scale Recognition Module
- - Real-time carrier recognition module considering NK cell size (20㎛)
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- MR Visualization Module
- - Visualization and simulation of medical microrobotics procedure
Solid Cancer
- Primary occurrence in specific organs such as liver, lungs,and brain
- Topical therapies such as surgical tumor removal and radiation therapy, and systemic therapy through drug administration
- Adverse events caused by peripheral tissue damage, toxicity, and non-selective delivery
Cell Therapy Procedures and Limitations
- Chemotherapy by Immune Cell Injection
- Repetitive or concurrent treatment with high cost, low directivity, and low cell activity due to tumor microenvironment
Medical Efficacy
- External electromagnetic drive module + NK cell carrier + Recognition visualization module
- Functional carrier to maintain cellular activity and inhibit cancer cells in solid cancer environment
- High-dose immune cell and drug delivery function
- Maximized treatment efficacy by external active driving and control by carrier
Optimized medical microrobotics Integrated System for Circulatory Diseases
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- Mobile Electromagnetic Actuation Module
- - Suitable for human length direction movement procedure (catheterization)
- Open structure that allows medical team collaboration
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- Ultrasonic Actuation Module
- - Focused drive of magnetic and nonmagnetic hemorrhagic embolism carrier
- Application on the bleeding area accessible by short distance drive
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- Hemorrhagic Embolism Carrier Module
- - Carrier module to treat bleeding of affected vessel
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- Micro-scale Recognition Module
- - Real-time carrier recognition module considering the hemorrhagic embolism carrier size (100um)
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- MR Visualization Module
- - Visualization and simulation of medical microrobotics procedure
Hemorrhagic Embolism
- Weak parts of the vessel wall swell due to blood pressure, causing rupture and bleeding.
- Needs to be fully blocked from normal blood flow.
Existing Surgical Procedures and Limitations
- Cervical aneurysm cerclage through surgery, aneurysm embolization using coil
- Difficulties with precise surgical procedure within the lesion Peripheral nerves, vascular rupture, perforation, embolism compression/deviation, recurrence, capillary occlusion
Medical Efficacy
- External electromagnetic driving device + hemorrhagic embolism carrier + recognition visualization module
- Complex hemostatic function by applying hydrogel and thrombosis agent (mechanical + pharmacodynamic)
- Precise movement and improved safety of procedure by targeting external drive in topical vessel
- No need for assisted procedure due to fixation in the lesion
Optimized medical microrobotics Integrated System for GastrointesitnalGastrointestinal Diseases
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- Mobile Electromagnetic Actuation Module
- - Actuation module for all digestive system diagnosis/treatment
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- Compound Eye Diagnosis Module
- - Digestive system diagnosis with lesion enlargement and virtual pigment imaging
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- Intestine Measurement Diagnosis Module
- - Combined sensor module for pH and pressure measurement inside the digestive system
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- Hemostatic Patch Module
- - Hemostatic agent carrying u-needle patch for digestive bleeding treatment
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- Microbial Collection Delivery Module
- - Multi-location targeting and multiple biome collection/storage/delivery module inside the digestive system
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- Reconstruction Assembly
- - Selective combination function of diagnostic/treatment module inside the organ
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- Meso-scale Recognition Module
- - 3D magnetic induced recognition module considering the diagnosis/treatment module size (mm)
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- MR Visualization Module
- - Visualization and simulation of medical microrobotics procedure
Digestive Disease
- Diagnosis and treatment using flexible endoscopy
- Utilization of imaging diagnosis with manual capsule endoscopy
- Flexible endoscopy: Sleep anesthesia, pain, unsanitary
- Manual capsule endoscopy: manual movement, real-time diagnosis not possible
Limit of the existing active capsule endoscopy
- In-vitro wireless control by a magnetic field
- Limited Real-time video diagnosis
- Lack of multifunctional diagnostic treatment procedure tool
- Low image resolution
- Limited size → Difficulty loading the
Medical Efficacy
- Mobile electromagnetic drive + diagnosis/treatment module + recognition visualization module
- Real-time precision diagnosis/treatment of all digestive organs
- Multifunction diagnostic/treatment module configuration
- Selective combination of functional modules in the organ
- Improvement of procedure convenience and safety
